Diagnosis of mild to moderate magnesium deficiency is challenging because patients may be asymptomatic, and usual diagnostic testing is specific but not sensitive. Some of the potential indications that require further investigation include lowering the risk of metabolic syndrome, treating leg cramps in pregnant women, preventing osteoporosis, and alleviating dysmenorrhea. 53 There are few studies to support wide use of magnesium for treating constipation and dyspepsia. The National Center for Complementary and Alternative Medicine is currently investigating the role of magnesium supplementation in mild to moderate persistent asthma. Magnesium is an essential mineral with evidence of effectiveness in treating eclampsia and preeclampsia, arrhythmia, severe asthma, and migraine ( Table 3). Mix in 4 oz water take up to three times per dayġ22 mg in 1,230 mg dietary supplement granules Magnesium aspartate hydrochloride (Maginex DS) One half to one full bottle (120 to 300 mL)Ĥ8 mg elemental magnesium and 13 mg potassium in 290 mg per 5 mL oral solutionĪtrial fibrillation: IV 1.2 to 5 g initial dose over one to 30 minutesĪsthma: IV 25 to 75 mg per kg single dose (study of children younger than 18 years)Įclampsia, preeclampsia: IV 4 to 6 g over15 to 20 minutes, then 1 to 2 g per hourĬathartic: mix 2 to 4 teaspoons in 8 oz water take up to twice per day Food sources of magnesium include green leafy vegetables, nuts, legumes, and whole grains.ĥ to 15 mL as needed up to four times per dayġ67 mg in 400 mg per 5 mL oral suspension Because magnesium is excreted renally, it should be used with caution in patients with kidney disease. Although it is safe in selected patients at appropriate dosages, magnesium may cause adverse effects or death at high dosages. The use of magnesium for constipation and dyspepsia are accepted as standard care despite limited evidence. Other areas that have shown promising results include lowering the risk of metabolic syndrome, improving glucose and insulin metabolism, relieving symptoms of dysmenorrhea, and alleviating leg cramps in women who are pregnant. Studies have shown the effectiveness of magnesium in eclampsia and preeclampsia, arrhythmia, severe asthma, and migraine. This has led to an increased awareness of proper magnesium intake and its potential therapeutic role in a number of medical conditions. Research has shown that the mineral content of magnesium in food sources is declining, and that magnesium depletion has been detected in persons with some chronic diseases. The variation in microstructural response with the orientation of loading allows for a wide range for tailoring mechanical properties of pure magnesium single crystals without any need of alloying.Magnesium is an essential mineral for optimal metabolic function. The microstructure studies by electron backscatter diffraction and XRD pole figure analysis revealed profuse ( $10\overline12$) twinning when compression is done along the growth plane (72 16 $\overline $ 15) was marked by a much lower degree of both twinning and recrystallization. Compressive testing along two orthogonal directions at low plastic strains was also performed. It was found by impact testing that the magnesium single crystal is highly ductile due to energy absorption by twinning and slip, while the polycrystalline samples fracture easily upon impact. This study describes results from mechanical tests conducted on magnesium single crystals in comparison with polycrystalline magnesium.
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